BBa_M50036
1
BBa_M50036
6 Amino Acid Fusion Protein Linker
2016-12-11T12:00:00Z
2016-12-11T04:55:01Z
Linker sequence was suggested and provided by our TA, Salil Bahte, and then optimized for use in E. coli.
This sequence encodes for six amino acids that constitute the fusion protein linker for our Stanford BioE44 DNA construct. It is optimized for use in E. coli, and is designed to maintain linearity of the sequence and prevent protein folding. Our design relied on proper orientation of two GBP domains linked on each end to a flurophore. The linkers were included to ensure that glucose-binding caused the conformational change characterized with FRET instead of inherently folded protein structure, the linkers were included.
false
false
_848_
34390
34390
9
false
Codon optimization software was used since we transformed our plasmid into E. coli. Also, the linker needed to be relatively short since we were already designing a long construct and needed to minimize the synthesis time given class constraints.
false
Amanda Urke
BBa_M50036_sequence
1
gggggcaccggcgggtcc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z