BBa_B0012
1
BBa_B0012
TE from coliphageT7
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Derived from the TE terminator of T7 bacteriophage between Genes 1.3 and 1.4 <genbank>V01146</genbank>.
Released HQ 2013
Transcription terminator for the <i>E.coli</i> RNA polymerase.
false
false
_1_
0
24
7
In stock
false
<P> <P>Suggested by Sri Kosuri and Drew Endy as a high efficiency terminator. The 5' end cutoff was placed immediately after the TAA stop codon and the 3' end cutoff was placed just prior to the RBS of Gene 1.4 (before AAGGAG).<P> Use anywhere transcription should be stopped when the gene of interest is upstream of this terminator.
false
Reshma Shetty
annotation7020
1
BBa_B0012
range7020
1
1
41
annotation1687
1
stop
range1687
1
34
34
annotation1690
1
polya
range1690
1
28
41
annotation1686
1
T7 TE
range1686
1
8
27
BBa_B0010
1
BBa_B0010
T1 from E. coli rrnB
2003-11-19T12:00:00Z
2015-08-31T04:07:20Z
Transcriptional terminator consisting of a 64 bp stem-loop.
false
false
_1_
0
24
7
In stock
false
true
Randy Rettberg
annotation7018
1
BBa_B0010
range7018
1
1
80
annotation4184
1
stem_loop
range4184
1
12
55
BBa_S04236
1
BBa_S04236
K237003:B0015
2009-08-02T11:00:00Z
2015-05-08T01:14:37Z
false
false
_9_
0
4087
9
Not in stock
false
false
Marc T. K. Nielsen
component2014724
1
BBa_B0010
component2014723
1
BBa_K237003
component2014726
1
BBa_B0012
annotation2014723
1
BBa_K237003
range2014723
1
1
90
annotation2014726
1
BBa_B0012
range2014726
1
187
227
annotation2014724
1
BBa_B0010
range2014724
1
99
178
BBa_K237003
1
sRIP
RIP +export signal (OmpA). Quorum sensing inhibitor of Staphylococcus spp. (Including MRSA)
2009-08-02T11:00:00Z
2015-05-08T01:11:36Z
The RIP peptide is produced by coagulase negative staphylococcus (suggested to be S. warnerii or S. xylosus) (16,19)
RIP or RNAIII inhibiting peptide is a heptapeptide capable of severely reducing the Qourum sensing(QS) abilities of Staphylococcus species. RIP effectively works as an antibiotic in its inhibition of bacterial growth.
RIP has the sequence YSPXTNF and has been tested extensively in a synthetic (as in organic) form for ability to inhibit bacterial infections in mice.
References will come later.
This is an export-tagged RIP brick. We used an OmpA tag, which (at least in theory) targets the peptide to the periplasmic space from where, there has been described numerous cases of leakage into the medium. Under the transport into the periplasmic space, the OmpA-leader should be cut off, leaving the RIP intact, and ready to inhibit some staph's.
We can at this point in our project not verify that RIP will be exported by our Coli's.
We have come to affectionately call this brick sRIP (short for signal-RIP, in contrast to just RIP).
false
false
_333_
0
4087
9
It's complicated
true
This sequence is reverse-engineered from the amino-acid sequence by using the commonly used codons of E. Coli.
It is designed to provide a big output of peptide. We just hope that this output won't kill the cell.
false
Marc T. K. Nielsen
annotation2014672
1
RIP
range2014672
1
64
84
annotation2014670
1
Stop
range2014670
1
85
89
annotation2014671
1
OmpA Leader
range2014671
1
4
63
annotation2014669
1
Start
range2014669
1
1
3
BBa_B0010_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctc
BBa_S04236_sequence
1
atgaaaaagacagctatcgcgattgcagtggcactggctggtttcgctaccgtagcgcaggcctattctccgtggaccaacttttaataatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_K237003_sequence
1
atgaaaaagacagctatcgcgattgcagtggcactggctggtttcgctaccgtagcgcaggcctattctccgtggaccaacttttaataa
BBa_B0012_sequence
1
tcacactggctcaccttcgggtgggcctttctgcgtttata
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z