BBa_S05048
1
BBa_S05048
B0034:K748000
2012-09-14T11:00:00Z
2015-05-08T01:14:48Z
Released HQ 2013
false
false
_9_
0
8564
9
In stock
false
false
Lei Qiao
component2183411
1
BBa_B0034
component2183412
1
BBa_K748000
annotation2183411
1
BBa_B0034
range2183411
1
1
12
annotation2183412
1
BBa_K748000
range2183412
1
19
648
BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_K748000
1
BBa_K748000
AgrA protein coding sequence. AgrA is the main component of S.aureus agr quorum sensing system.
2012-09-14T11:00:00Z
2015-05-08T01:13:12Z
Staphylococcus aureus genomic sequence
Staphylococcus aureus AgrA, the transcriptional component of a quorum sensing system and global regulator of virulence that up-regulates secreted virulence factors and down-regulates cell wall-associated proteins, can bind in both the P2 and P3 promoter regions of the agr locus. The composite of AgrC and AIP then leads to phosphorylation of AgrA. AgrA in its phosphorylated sate activates transcription from both P2 and P3, leading to the production of GFP and 3OC6HSL. Thus we can detect the presence of S.aureus expediently by observing the expression of GFP.
false
false
_999_
0
8564
9
It's complicated
false
As a AIP sensor system, agrA should work with agrC.
false
Lei Qiao
BBa_B0034_sequence
1
aaagaggagaaa
BBa_S05048_sequence
1
aaagaggagaaatactagatggaaattgcattagcaacagataatccatatgaagttttagaacaagcaaaaaatatgaatgatattggttgttattttttagatattcaattatcaacagatattaatggtattaaattaggttcagaaattcgtaaacatgatccagttggtaatattatttttgttacatcacattcagaattaacatatttaacatttgtttataaagttgcagcaatggattttatttttaaagatgatccagcagaattacgtacacgtattattgattgtttagaaacagcacatacacgtttacaattattatcaaaagataattcagttgaaacaattgaattaaaacgtggttcaaattcagtttatgttcaatatgatgatattatgttttttgaatcatcaacaaaatcacatcgtttaattgcacatttagataatcgtcaaattgaattttatggtaatttaaaagaattatcacaattagatgatcgtttttttcgttgtcataattcatttgttgttaatcgtcataatattgaatcaattgattcaaaagaacgtattgtttattttaaaaataaagaacattgttatgcatcagttcgtaatgttaaaaaaatttaataa
BBa_K748000_sequence
1
atggaaattgcattagcaacagataatccatatgaagttttagaacaagcaaaaaatatgaatgatattggttgttattttttagatattcaattatcaacagatattaatggtattaaattaggttcagaaattcgtaaacatgatccagttggtaatattatttttgttacatcacattcagaattaacatatttaacatttgtttataaagttgcagcaatggattttatttttaaagatgatccagcagaattacgtacacgtattattgattgtttagaaacagcacatacacgtttacaattattatcaaaagataattcagttgaaacaattgaattaaaacgtggttcaaattcagtttatgttcaatatgatgatattatgttttttgaatcatcaacaaaatcacatcgtttaattgcacatttagataatcgtcaaattgaattttatggtaatttaaaagaattatcacaattagatgatcgtttttttcgttgtcataattcatttgttgttaatcgtcataatattgaatcaattgattcaaaagaacgtattgtttattttaaaaataaagaacattgttatgcatcagttcgtaatgttaaaaaaatttaataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z