BBa_I10021

BBa_I10021 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_I10021
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Angela Wu
Date created: 2006-04-12 11:00:00
Date modified: 2015-08-31 04:07:29

Renin



Types
DnaRegion

Roles
CDS

Coding

Sequences BBa_I10021_sequence (Version 1)

Description

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Mutations in this gene have been shown to cause familial hyperproreninemia.

igem#sampleStatus
Not in stock
igem#status
Unavailable
 
synbiohub#ownedBy
user/james
 
synbiohub#ownedBy
user/myers
 
synbiohub#topLevel
BBa_I10021/1