Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Lissa Riley
Date created: 2006-04-11 11:00:00
Date modified: 2015-08-31 04:07:29
Perforin
| Types | DnaRegion |
| Roles | Coding CDS |
| Sequences | BBa_I10117_sequence (Version 1) |
Description
This is the gene for perforin. It inserts itself in to a cell's plasma membrane and causes lysis for a wide variety of cell types. It might only work if granzyme is also present.The protein is 555 amino acids long.
The gene contains 3 exons.
After *extensive* searching, there appears to be disagreement on the ORF length. Several sources cite a transcript of length ~4 kbp, but ORF Finder gives nothing longer than ~1.2 kbp.