Types | DnaRegion
|
Roles | CDS
Coding
|
Sequences | BBa_K1061003_sequence (Version 1)
|
Description
Receptor interacting protein 3, also a serine/threonine kinase that play an important role in cell apoptosis and necrosis. It can induce necrosis via the interaction with RIP 1.
Notes
Although RIP 3 can also induce apoptosis, it mainly induces necrosis via interaction with RIP 1. So the mammalian circuit that aid to use in clinical should use tightly control expression device.
Source
We clone this gene by RT-PCR.