Types | DnaRegion
|
Roles | Coding
CDS
|
Sequences | BBa_K1074009_sequence (Version 1)
|
Description
Killing factor of Bacillus subtilis ,SpbC Induces the lysis of other B.subtilis cells that have not entered the sporulation pathway, providing a source of nutrients to support sporulation. Its maturation is dependent on SdpA and SdpB. Also functions as a ligand, being able to bind to SdpI thereby triggering a signal transduction cascade that protects the cell against the toxic effects of its own SdpC.
We use this killing factor to build a kill switch for Bacillus subtilis.
Notes
With restriction sites of Spe I and Pst I in the sequence.
Source
From the genome of Bacillus subtilis (strain 168)