| Types | DnaRegion
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| Roles | Coding
CDS
|
Description
This is an ancestrally predicted version of the CysE gene, which is involved in amino acid synthesis. CysE is responsible for synthesizing cysteine. This ancestral version was predicted using the representative data from Pfam (PF06426) and PAML with the Lazarus suite. This Pfam data included only the N-terminal of the gene. The part here includes the predicted ancestral N-terminal fused with the remainder of the CysE gene from E coli (K12).
Notes
Design considerations included figuring out how to combine a partial prediction of this gene (the N-terminal) with the remaining region of the gene from E coli (K12).
Source
This version of CysE is a predicted ancestral sequence. It comes from a prediction made using Pfam seed data (PF06426) as an input for PAML with Lazarus, which is used to predict sequences of a common ancestor. This process makes up the N-terminal. The rest of the gene is the wild type found in E coli (K12).
