Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Andr??s Ferri??o Iriarte
Date created: 2013-09-07 11:00:00
Date modified: 2015-05-08 01:09:44
MarA Generator
| Types | DnaRegion |
| Roles | Generator engineered_region |
| Sequences | BBa_K1230004_sequence (Version 1) |
Description
The MarA protein acts as a transcriptional activator in E. coli. It allows the expression of the acrAB and tolC operons, which activate the AcrAB-TolC efflux pump, a mechanism that has been related with resistance to organic solvents, dyes, detergents, antibiotics such as chloramphenicol, tetracycline, novobiocin, erythromycin, fusidic acid and cloxacillin, as well as to cationic antimicrobial peptides, such as LL-37, HNP-2 and HBD-1.This composite part allows MarA expression in presence of IPTG, by using the LacI promoter and the RBS based on Elowitz repressilator (Part BBa_J04500)
Notes
We ligated part BBa_K875009 as a prefix and part BBa_E0840 as a suffix.Source
2013 DNA distribution and synthesis by genscript.| Access | Instance | Definition |
| public public | BBa_J04500 BBa_K1230000 | BBa_J04500 MarA |
| Sequence Annotation | Location | Component / Role(s) |
| BBa_J04500 BBa_K1230000 | 1,220 227,619 | BBa_J04500 MarA |