| Types | DnaRegion
|
| Roles | Plasmid
plasmid
|
| Sequences | BBa_K1391006_sequence (Version 1)
|
Description
Spleen Tyrosine Kinase (Syk) is a tyrosine kinase that has a high affinity for the phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) of the CD79A and CD79B proteins (components of the B-Cell Receptor Complex). Syk binds to the phosphorylated ITAM and the ITAM then phosphorylates Syk allowing Syk to initiate a downstream signalling cascade that ordinarily results in the proliferation of B-Cells during clonal selection.
Notes
None
Source
Human genome
