Types | DnaRegion
|
Roles | Coding
CDS
|
Sequences | BBa_K1393003_sequence (Version 1)
|
Description
One OmpC molecule consists of 16 transmembrane, antiparallel β-strands, which produce a β-barrel structure surrounding a large channel and are connected by seven internal loops and eight external loops. Three OmpC molecules form a pore structure on the outer membrane of an E.coli cell, which allows small hydrophilic molecules to pass through.
Notes
In general, the amino acid sequences of the external loops are less conservative, and thus these loops may be relatively tolerant to insertion and deletion. We used the external loop as the point of insertion for foreign peptides (copper binding polypeptide or polyhistidine) for cell surface display.
Source
This part is from genome of Escherichia coli BL21(DE3).