Types | DnaRegion
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Roles | Protein_Domain
polypeptide_domain
|
Sequences | BBa_K1423000_sequence (Version 1)
|
Description
This part is the N-terminal domain of BCLA, and it can be used as an anchoring motif for cell surface display. BCLA is a hair-like glycoprotein found on the outermost layer of the Bacillus anthracis spore. It consists of three parts: an N terminal domain, a central domain (also called collagen-like region ???CLR???), and a C terminal domain. A picture of the structure of BCLA can be seen below.
Notes
When designing the part we ensured that BCLA and any following parts would remain in frame. This is essential because as an anchoring motif we expect additional domains to be attached after.
Source
Bacillus anthracis