Types | DnaRegion
|
Roles | CDS
Coding
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Sequences | BBa_K156000_sequence (Version 1)
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Description
This codes for the protein PhaA (acetyl-CoA acetyltransferase, GeneID:4249783), which converts acetyl-CoA to acetoacetyl-CoA. This is the first step in the production of the bioplastic Polyhydroxybutyrate (PHB).
Notes
Once the sequence was obtained from the literature, we simply codon optimized it for E coli to maximize production.
Source
This comes from the organism Ralstonia eutropha, which naturally produces PHB. The sequence has been codon optimized for use in E coli.