BBa_K1588009

BBa_K1588009 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_K1588009
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Juan David Sifontes
Date created: 2015-09-17 11:00:00
Date modified: 2015-09-18 08:39:10

Protein with epitopes from dengue virus serotype 4 to generate immune response



Types
DnaRegion

Roles
DNA

sequence_feature

Sequences BBa_K1588009_sequence (Version 1)

Description

it is a gene coding a modified Chitin Oligosaccharide Binding Protein (code 1ZTY) from Vibrio cholerae, we cut some residues from external loops and inserted human epitopes from serotype 4 of dengue virus instead, it is intended to generate an immune response against all serotypes of the virus, those epitopes come from T lymphocytes, it could be improved inserting epitopes from B lymphocytes

Notes

1. It is coded by just one gene
2. Is not too big
3. It is exported by bacterial cells
4. Has big hydrophylic loops to insert epitopes

Source

Vibrio cholerae VC_0620

Sequence Annotation Location Component / Role(s)
Protein den 4
1,1743
feature/dna sequence_feature
igem#status
Planning
 
synbiohub#ownedBy
user/james
 
synbiohub#ownedBy
user/myers
 
synbiohub#topLevel
BBa_K1588009/1