BBa_K1588009

BBa_K1588009 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K1588009

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Juan David Sifontes

Date created: 2015-09-17 11:00:00

Date modified: 2015-09-18 08:39:10

Protein with epitopes from dengue virus serotype 4 to generate immune response

Details

• Types: DnaRegion
• Roles: DNA; sequence_feature
• Sequences: BBa_K1588009_sequence (Version 1)

Description

it is a gene coding a modified Chitin Oligosaccharide Binding Protein (code 1ZTY) from Vibrio cholerae, we cut some residues from external loops and inserted human epitopes from serotype 4 of dengue virus instead, it is intended to generate an immune response against all serotypes of the virus, those epitopes come from T lymphocytes, it could be improved inserting epitopes from B lymphocytes

Notes

1. It is coded by just one gene
2. Is not too big
3. It is exported by bacterial cells
4. Has big hydrophylic loops to insert epitopes

Source

Vibrio cholerae VC_0620

Sequence Annotations

Sequence Annotation	Location	Component / Role(s)
Protein den 4	1,1743	feature/dna, sequence_feature

Other Properties

• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K1588009/1

Member of these Collections

• iGEM Parts Registry