BBa_K1611002

BBa_K1611002 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_K1611002
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Frederic Ros
Date created: 2015-09-14 11:00:00
Date modified: 2015-12-17 01:04:22

OVA1



    • Details

    Types
    DnaRegion

    Roles
    CDS

    Coding

    Sequences BBa_K1611002_sequence (Version 1)

    Description

    OVA1 is an antigen expressed in tumor melanocytes cell line B16-OVA1. In the immune system, it is presented by the MHC-I to activate T-CD8 cells. It activated CD8+ in vivo against OVA1 in C57BL/6 mice, as tetramer CD8+ assays demonstrated.

    Notes

    Nothing to signal.

    Source

    OVAI was synthesized by the epitope SIINFEKL + surrounding residues to allow better processing by the immunoproteasome.

    Sequence Annotation Location Component / Role(s)
    start
    cds
    stop
    		1,3
    1,63
    61,66
    		start_codon feature/start
    CDS feature/cds
    feature/stop stop_codon

    igem#status
    Planning
     
    synbiohub#ownedBy
    user/james
     
    synbiohub#ownedBy
    user/myers
     
    synbiohub#topLevel
    BBa_K1611002/1
     

    Attachments

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