| Types | DnaRegion
|
| Roles | promoter
Regulatory
|
| Sequences | BBa_K1922001_sequence (Version 1)
|
Description
This is a promoter starting the expression of telomerase,an important enzyme to keep the telomere from being shortern during the cell proliferation.Since the tumor cell requires rapid cell proliferation,the content of telomerase is usually detected higher than normal cell.Therefore, we can use the Htert promoter as a cancer specific promoter to start downstream gene expresses only in tumor cell.
Notes
Since the tumor cell requires rapid cell proliferation,the content of telomerase is usually detected higher than normal cell.As a result,the expressing components for Htert promoter is more in tumor cells.Therefore, we can use the Htert promoter as a cancer specific promoter to start downstream gene expression only in tumor cell.
Source
This part comes from genomic sequence from tumor cell.
