BBa_K1932004

BBa_K1932004 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K1932004

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Jin Liu

Date created: 2016-10-13 11:00:00

Date modified: 2016-10-16 02:06:44

TAT+apoptin

Details

• Types: DnaRegion
• Roles: Coding; CDS
• Sequences: BBa_K1932004_sequence (Version 1)

Description

TAT-Apoptin is a fusion protein made up of the transduction domain of HIV-1 and apoptin. Since apoptin only functions inside the cells, the peptide TAT is added to direct the transfer of the apoptin into the cell. Once transferred into the tumor cells, apoptin can induce the apoptosis of them potently.

Notes

(1) The restriction enzyme cutting site was identified.
(2) The appropriate sequences of TAT and apoptin were selected.

Source

HIV-1 and CAV

Sequence Annotations

Sequence Annotation	Location	Component / Role(s)
TAT	1,36	CDS, feature/protein
linker	37,66	feature/binding, non_covalent_binding_site
apoptin	67,432	feature/protein, CDS

Other Properties

• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K1932004/1

Member of these Collections

• iGEM Parts Registry