Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Emilie Gounin
Date created: 2016-10-12 11:00:00
Date modified: 2016-10-13 06:37:51
White collar-2 (WC-2) - photoreceptor in Neurospora tetrasperma
| Types | DnaRegion |
| Roles | CDS Coding |
| Sequences | BBa_K1935005_sequence (Version 1) |
Description
May function as a transcription factor involved in light regulation. Binds and affects blue light regulation of the al-3 gene. Wc-1 and wc-2 interact via homologous PAS domains, bind to promoters of light regulated genes such as frq, and activate transcription. May bind directly to frq.WC-1 and WC-2 are transcription factors encoded by the genes wc-1 and wc-2. Zinc finger DNA-binding domains allow WC-1 and WC-2 to bind to DNA and act as transcription factors. Both WC-1 and WC-2 have PAS domains that allow them to bind to other proteins. WC-1 and WC-2 typically heterodimerize in vivo to form the White Collar Complex (WCC), which acts as a transcription factor complex. In vitro, WC-1 can also homodimerize with itself and heterodimerize with other PAS proteins. WC-1 and WC-2 bind to the promoter elements of the genes that they transcriptionally activate. Function in the circadian clock.