CDO

BBa_K2004007 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K2004007

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Marco V. Lincango Y.

Date created: 2016-10-17 11:00:00

Date modified: 2016-10-18 11:17:59

Cysteine dioxygenase (CDO)

Details

• Types: DnaRegion
• Roles: CDS; Coding
• Sequences: BBa_K2004007_sequence (Version 1)

Description

Cysteine dioxygenase (CDO, 2 EC 1.13.11.20) is a non-heme mononuclear iron metalloenzyme that catalyzes the irreversible oxidation of cysteine to cysteine sulfinic acid (CSA) with addition of molecular oxygen. This enzyme has a length of 200 aminoacids and a mass of 22,972 Daltons (UniProt, 2005).

The product of the reaction catalyzed by CDO, cysteine sulfinic acid, is either decarboxylated to hypotaurine, which is further oxidized to taurine by a poorly understood mechanism.

Notes

This sequence was optimized to be able to use in E. coli in addition to be free of restriction sites into the coding region. This biobrick can be used in RFC 10.

Source

The sequence of this part was taken from the NCBI databank, and the original sequence belongs to Enterobacter aerogenes.

Other Properties

• igem#experience: None
• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K2004007/1

Member of these Collections

• iGEM Parts Registry