| Types | DnaRegion
|
| Roles | mature_transcript_region
RNA
|
| Sequences | BBa_K2050424_sequence (Version 1)
|
Description
The VA1 RNA gene is an RNA polymerase III-driven gene that encodes the viral RNA VA1. By its nature, the RNA molecule facilitates infection by inhibiting the protein kinase R response, which is activated in infected cells and acts to globally suppress gene expression to inhibit viral replication. Co-expressing the VA1 RNA gene with a desired non-coding RNA gene allows for the expression of the desired RNA molecule, which would generally trigger PKR response, without sacrificing RNA polymerase II transcription.
Notes
None
Source
The sequence is bases 10597 to 10790 of the Ad5 genome (GenBank accession number X02996).
