Types | DnaRegion
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Roles | tag
Tag
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Sequences | BBa_K210004_sequence (Version 1)
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Description
PEST sequence is degradation tag for eucaryote. This is a peptide sequence which is rich in proline (P), glutamic acid (E), serine (S), and threonine (T). This sequence is associated with proteins that have a short intracellular half-life; hence, it is hypothesized that the PEST sequence acts as a signal peptide for protein degradation.
The degradation may be mediated possibly via the proteosome or calpain.
Notes
This parts has Pst1 recognition site.
Source
pd2EGFP-Basic