BBa_K2136002

BBa_K2136002 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K2136002

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Livia Seno Ferreira Camargo

Date created: 2016-10-12 11:00:00

Date modified: 2016-10-18 03:16:56

Lysostaphin

Details

• Types: DnaRegion
• Roles: Protein_Domain; polypeptide_domain
• Sequences: BBa_K2136002_sequence (Version 1)

Description

Lysostaphin is a zinc metalloproteinase (EC 3.4.24.75) produced by Staphylococcus simulans. This enzyme hydrolyses Glycine/Glycine bonds in the pentaglycine interpeptide that maintain the stability of peptidoglycans in staphylococcal cell wall [1]. Lysostaphin rapidly lyses actively growing and non-dividing cells including staphylococci in biofilms and due to its specificity, it could have high potential in the treatment of antibiotic-resistant staphylococcal infections [2]

Notes

Codon optimization for Chlamydomonas reinhardtii

Source

This enzybiotic sequence was taken from the microorganism Staphylococcus simulans and Synthesized by IDT.

Sequence Annotations

Sequence Annotation	Location	Component / Role(s)
Protein domain	1,738	feature/protein, CDS

Other Properties

• igem#experience: None
• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K2136002/1

Member of these Collections

• iGEM Parts Registry