BBa_K2170210

BBa_K2170210 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_K2170210
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: LMU_TUM_Munich
Date created: 2016-09-11 11:00:00
Date modified: 2016-10-10 11:28:03

Epidermal growth factor receptor transmembrane domain (EGFR TMD) in RFC[25]



Types
DnaRegion

Roles
polypeptide_domain

Protein_Domain

Sequences BBa_K2170210_sequence (Version 1)

Description

This part encodes for the epidermal growth factor receptor (EGFR) transmembrane domain (TMD). The EGFR stop transfer signal in the 3' region of the TMD increases the membrane stability. The part is ideal for combining internal and external membrane domains to one fusion protein. The glycine linkers in the 5' and 3' region of the part lead to a better flexibility and a better performance of the fused parts.

The part is flanked by RFC25 pre- and suffix for further use in proteinfusion.

Notes

.

Source

The part was ordered as genesynthesis from IDT, codonoptimized for H. sapiens and cloned on pSB1C3.

igem#experience
None
 
igem#status
Planning
 
synbiohub#ownedBy
user/james
 
synbiohub#ownedBy
user/myers
 
synbiohub#topLevel
BBa_K2170210/1