Types | DnaRegion
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Roles | polypeptide_domain
Protein_Domain
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Sequences | BBa_K2170210_sequence (Version 1)
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Description
This part encodes for the epidermal growth factor receptor (EGFR) transmembrane domain (TMD). The EGFR stop transfer signal in the 3' region of the TMD increases the membrane stability. The part is ideal for combining internal and external membrane domains to one fusion protein. The glycine linkers in the 5' and 3' region of the part lead to a better flexibility and a better performance of the fused parts.
The part is flanked by RFC25 pre- and suffix for further use in proteinfusion.
Notes
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Source
The part was ordered as genesynthesis from IDT, codonoptimized for H. sapiens and cloned on pSB1C3.