MBP

BBa_K231000 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_K231000
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Daniel R Tarjan
Date created: 2009-10-20 11:00:00
Date modified: 2015-07-21 02:28:52

Metal binding peptide



Types
DnaRegion

Roles
Coding

CDS

Sequences BBa_K231000_sequence (Version 1)

Description

This part codes for a peptide containing a metal binding motif. De novo design allows this peptide to have high affinity for metals. Affinity derives from Cys-Gly repeats. This peptide encodes two Cys-Gly-Cys-Cys-Gly repeats. Other metals besides arsenic, such as Cd and Hg, should be bound as well.

Notes

This peptide only contains two repeats of the metal binding motif due to size limitations when ordering oligos. Further repeats of the binding motif may enhance its function.

Source

Derived from peptide described in: Pazirandeh et al. Development of Bacterium-Based Heavy Metal Biosorbents: Enhanced Uptake of Cadmium and Mercury by Escherichia coli Expressing a Metal Binding Motif. Applied and Environmental Microbiology, October 1998, p. 4068-4072, Vol. 64, No. 10

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BBa_K231000/1