ComD

BBa_K316015 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_K316015
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: IC 2010 Team
Date created: 2010-10-19 11:00:00
Date modified: 2015-05-08 01:11:56

ComD receptor for CSP-1 (S. pneumoniae), phosphorylates ComE



Types
DnaRegion

Roles
Translational_Unit

engineered_region

Sequences BBa_K316015_sequence (Version 1)

Description

ComD is the histidine kinase of a two-component signal transduction signaling pathway in a Streptococcus pneumoniae quorum sensing system. It detects the linear autoinducing peptide (AIP) called Competence-Stimulating Peptide-1 (CSP-1) which is coded for by the ComC gene. Upon detection of CSP-1, ComD will autophosphoylate and then phosphorylate and activate the response regulator, ComE

Notes

The part contains a synthetic RBS optimised for high expression in B subtilis, calculated using RBS calculator [ link ]

Source

Streptococcus pneumoniae, AAC44896.1, codon optimised for expression in B.subtilis

Sequence Annotation Location Component / Role(s)
RBS ComD
start codon of ComD
stop codon
Coding Region
1,10
18,20
1371,1373
18,1370
engineered_region feature/BioBrick
feature/start start_codon
feature/stop stop_codon
feature/protein CDS
igem#experience
None
 
igem#sampleStatus
It's complicated
igem#status
Planning
 
synbiohub#ownedBy
user/james
 
synbiohub#ownedBy
user/myers
 
synbiohub#topLevel
BBa_K316015/1