BBa_K364308

BBa_K364308 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K364308

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Bence Daniel

Date created: 2010-09-27 11:00:00

Date modified: 2015-05-08 01:12:14

Human PXR LBD

Details

• Types: DnaRegion
• Roles: Coding; CDS
• Sequences: BBa_K364308_sequence (Version 1)

Description

Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds.
Activated by naturally occurring steroids, such as pregnenolone and progesterone.

Notes

The reconstruction of the DBD to the hinge region, LBD and Backbone will be done with RFC 25

Source

Human PXR(of the nuclear hormone receptor superfamily)

Other Properties

• igem#experience: Works
• igem#sampleStatus: It's complicated
• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K364308/1

Member of these Collections

• iGEM Parts Registry