BBa_K364310

BBa_K364310 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_K364310
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Lior Malka
Date created: 2010-09-28 11:00:00
Date modified: 2015-05-08 01:12:14

EcR LBD



    • Details

    Types
    DnaRegion

    Roles
    CDS

    Coding

    Sequences BBa_K364310_sequence (Version 1)

    Description

    The ecdysone receptor is a nuclear receptor found in arthropods, where it controls development and contributes to other processes such as reproduction.
    The receptor is a non-covalent heterodimer of two proteins, the EcR protein and ultraspiracle protein (USP). It binds to and is activated by ecdysteroids.
    Pulses of 20-hydroxyecdysone occur during insect development, whereupon this hormone binds to the ecdysone receptor, a ligand-activated transcription factor found in the nuclei of insect cells. This in turn leads to the activation of many other genes,WHICH Ultimately causes physiological changes that result in ecdysis (moulting).

    Notes

    The reconstruction of the DBD to the hinge region, LBD and Backbone will be done with RFC 25

    Source

    Human EcR (of the nuclear hormone receptor superfamily)

    igem#experience
    Works
     
    igem#sampleStatus
    It's complicated
    igem#status
    Planning
     
    synbiohub#ownedBy
    user/james
     
    synbiohub#ownedBy
    user/myers
     
    synbiohub#topLevel
    BBa_K364310/1
     

    Attachments

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