BBa_K518003

BBa_K518003 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K518003

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Masato Ohgishi

Date created: 2011-09-14 11:00:00

Date modified: 2015-05-08 01:12:33

LexA - a repressor for LexA-regulated SOS promoters -

Details

• Types: DnaRegion
• Roles: CDS; Coding
• Sequences: BBa_K518003_sequence (Version 1)

Description

Escherichia coli and other organisms have a gene cluster activated in case of emergency, which is called "SOS genes". It is well-documented that in E. coli, most of those SOS genes are repressed by LexA protein. When the cell is exposed to excess stress, RecA is up-produced, which promotes the self-degradation of LexA. As a result, many LexA-regulated genes become expressed.
Combined with RecA () and SOS promoters (for instance, ), a stress-responsive gene-expression circuit was assembled. See ().

Notes

None.

Source

Cloned de novo from Escherichia coli JM109 strain.

Other Properties

• igem#sampleStatus: It's complicated
• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K518003/1

Member of these Collections

• //cds/transcriptionalregulator/repressor
• iGEM Parts Registry