Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Masato Ohgishi
Date created: 2011-09-26 11:00:00
Date modified: 2015-05-08 01:12:33
recN promoter
| Types | DnaRegion |
| Roles | Regulatory promoter |
| Sequences | BBa_K518011_sequence (Version 1) |
Description
Microbes including Escherichia coli are known to respond to various DNA-injuring stress (ionizing radiation, ultraviolet radiation, peroxides etc...), altering their gene expressions. This response, known as "SOS response", are induced by regulatory protein called RecA, which is activated when binds to single-strand DNA. DNA-RecA complex promotes the self-degradation of LexA, a common repressor for SOS genes.RecN is involved in repair of double strand breaks in the chromosome. The promoter of recN, or recNp, is acutely induced by various stress factors.