| Types | DnaRegion
|
| Roles | engineered_region
Composite
|
| Sequences | BBa_K544003_sequence (Version 1)
|
Description
The tetR-HNS2-90 protein fuses the polymerization demain of histone-like nucleoid-structuring (H-NS) protein to tetR. Thus, in E.coli, when TetR-HNS2-90 binds the TetR-specific DNA motif, it will recruit native H-NS to bind to adjacent DNA, which may lead to local gene silencing. This fusion protein is driven by constitutive promoter family members (BBa-J23103, BBa-J23109, BBa-J23116, and BBa-J23106). Experimental data indicates that TetR-HNS2-90 is more effective than TetR on transcription repression.
Notes
The source of this part is based on the registry distribution
Source
The source of this part is based on the parts in the registry distribution
