BBa_K565004

BBa_K565004 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K565004

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Juan Ricardo Ortiz Meneses

Date created: 2011-09-17 11:00:00

Date modified: 2015-05-08 01:12:42

Microcin C51 production device

Details

• Types: DnaRegion
• Roles: engineered_region; Composite
• Sequences: BBa_K565004_sequence (Version 1)

Description

Microcin C51 is a bacteriocin protein produced by the Escherichia coli pMccC51 plasmid. They make holes in bacterial membranes.

In our project, we used Microcin C51 to kill pathogen cells (in our case they were E. coli DH5alpha strain) by membrane lysis, disinfecting the contaminated water.

Notes

Please see K. Severinov et al. PROKARYOTIC ANTIMICROBIAL PEPTIDES, 2011, Part 5, 289-308, Class I Microcins: Their Structures, Activities and Mechanisms of Resistance., for info on this point.

Source

The sequence of the Escherichia coli pMccC51 plasmid mccABCDE genes have been deposited under the accession numbers AJ487788.2, in the EMBL/GenBank database.
This part was central in our 2011 iGEM project: http://2011.igem.org/Team:Valencia

Other Properties

• igem#experience: Issues
• igem#sampleStatus: It's complicated
• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K565004/1

Member of these Collections

• iGEM Parts Registry