G319S_Tri

BBa_K590022 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_K590022
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Sydney Gordon, Daniel Hadidi, Elizabeth Stanley, Sarah Wolf, Angus Toland, Sean Wu
Date created: 2011-09-14 11:00:00
Date modified: 2015-05-08 01:12:47

Kumamolisin-As_G319S, D358G, D368H



Types
DnaRegion

Roles
CDS

Coding

Sequences BBa_K590022_sequence (Version 1)

Description

A mutated Kumamolisin-As enzyme aimed to combat celiac disease by increased specificity for the PQLP peptide, an antigenic epitope in gliadin.

Notes

Point mutation at residues 319, 358, and 368 from Glycine to Serine, Aspartate to Glycine, and Aspartate to Histidine, respectively.

Source

In-House Mutant

igem#experience
Works
 
igem#sampleStatus
In stock
igem#status
Available
 
synbiohub#ownedBy
user/james
 
synbiohub#ownedBy
user/myers
 
synbiohub#topLevel
BBa_K590022/1