| Types | DnaRegion
|
| Roles | Coding
CDS
|
| Sequences | BBa_K644001_sequence (Version 1)
|
Description
HWP1 is a Candida albicans cell surface protein gene. It is used in Candida albicans to mediate tight binding to oral epithelial cells. Hwp1 is covalently linked to cell wall glucan through a remnant of its GPI anchor. (Eukaryot Cell. 2006 October; 5(10): 1604???1610.) Hwp1 is known to cause biofilm formation in vivo in C. albicans.
Notes
Since there is an EcoRI restriction endonuclease site on the HWP1 gene sequence, we had to use the Gibson Assembly method to clone the HWP1 gene into the BioBrick plasmid pSB1C3.
Source
Candida albicans
