| Types | DnaRegion
|
| Roles | Coding
CDS
|
| Sequences | BBa_K861030_sequence (Version 1)
|
Description
For a E.coli to degrade fatty acid, at least four enzymes ??? FadA, FadB, FadD, FadE and a transporter???FadL are needed. Long chain fatty acids are firstly being imported by the transmembrane protein FadL. After FAs get into cells, they will be added to a CoA by inner membrane-associated FadD (acyl-CoA synthase). β-oxidation is initiated by FadE(acyl-CoA dehydrogenase), which will convert acyl-CoA into enoyl-CoA. The following cycles of hydration, oxidation, and thiolytic cleavage are carried out by tetrameric complex consisting of two FadA and two FadB proteins.
Notes
None
Source
E.coli str.K12 lab mutant DH5α
