Types | DnaRegion
|
Roles | CDS
Coding
|
Sequences | BBa_K929105_sequence (Version 1)
|
Description
A human immunoglobulin gamma-1 heavy chain constant region (IGHG1) was added to the construct and enables the direct interaction of the antibody unit with the Fc receptor and complement proteins.
Notes
Gene synthesis by GeneArt, optimized for expression in CHO cells (Cricetulus griseus).
Source
Fc domain: human immunoglobulin gamma-1 heavy chain constant region taken from GenBank: J00228.1 (UniProt: P01857), gene synthesis by GeneArt, optimized for expression in CHO cells (Cricetulus griseus)