| Types | DnaRegion
|
| Roles | CDS
Coding
|
| Sequences | BBa_K932001_sequence (Version 1)
|
Description
EnvZ is a histidine kinase/phosphatase that regulates the phosphorylation state of the transcription factor OmpR, controlling the downstream expression of outer membrane porins OmpF and OmpC and the csgD regulon for production of the curli cluster proteins.
Notes
The intention is for production of this protein to amplify expression of the curli cluster. Detailed design required consideration of the interactions of downstream proteins of EnvZ (its regulation of OmpR and subsequent modulation of a number of downstream transcriptional activities). This protein acts in a single-input module network motif.
Source
E. coli K-12 strain MG1655
