Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Ashton Young
Date created: 2009-04-14 11:00:00
Date modified: 2015-05-08 01:13:52
pyruvate decarboxylase
| Types | DnaRegion |
| Roles | sequence_feature DNA |
| Sequences | BBa_M11041_sequence (Version 1) |
Description
Pyruvate decarboxylase is a homotetrameric enzyme that catalyses the decarboxylation of pyruvic acid to acetaldehyde and carbon dioxide. It is also called 2-oxo-acid carboxylase, alpha-ketoacid carboxylase, and pyruvic decarboxylase. In aerobic conditions, this enzyme is the first in a three enzyme complex known as the pyruvate dehydrogenase complex, which converts pyruvate (the product of glycolysis) into acetyl CoA. In anaerobic conditions, this enzyme is part of the fermentation process that occurs in yeast, especially of the Saccharomyces genus, to produce ethanol alcohol by fermentation. Pyruvate decarboxylase starts this process by converting pyruvate into acetaldehyde and carbon dioxide. To do this, two thiamine pyrophosphate (TPP) and two magnesium ions are required as a cofactors. This enzyme should not be mistaken for the unrelated enzyme pyruvate dehydrogenase, an oxidoreductase, that catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA.Notes
NoneSource
Zymomonas mobilis mobilis ZM4| Sequence Annotation | Location | Component / Role(s) |
| start stop pRBS-SD+7Nde stop pyruvate decarboxylase | 14,16 1718,1720 1,13 1721,1723 14,1717 | feature/start start_codon feature/stop stop_codon feature/rbs ribosome_entry_site stop_codon feature/stop CDS feature/protein |