| Types | DnaRegion
|
| Roles | DNA
sequence_feature
|
| Sequences | BBa_M36560_sequence (Version 1)
|
Description
This is the cDNA Sequence of the human ESR2 (or ER-Beta) gene. It encodes for a protein which responds to estrogen (specifically estradiol) levels in the cells environment.
Notes
In finding the ESR2 coding sequence, we had to be sure to use the cDNA sequence as that would not need to be cut apart as a full cDNA sequence would. Using the cDNA sequence made our part shorter and increased its versatility, as it could now be used in prokaryotic cells.
Source
This sequence comes from human DNA, but the sequence used in the part is the cDNA format in oder to avoid the necessity of splicing the mRNA produced before translation (something that prokaryotic cells are not capable of). The cDNA sequence was obtained from the website www.sinobiological.com and the link to the specific page is listed here: http://www.sinobiological.com/ESR2-cDNA-Clone-g-2579.html
