Types | DnaRegion
|
Roles | Regulatory
promoter
|
Sequences | BBa_M36562_sequence (Version 1)
|
Description
This part is a short sequence that the estrogen receptor beta attaches to after it detects estrogen and forms a homodimer. When bound to this ERE site, the estrogen receptor can activate or deactivate transcription.
Notes
We used the sequence CTG as the "NNN" in the center of the sequence design.
Source
The sequence we used was obtained from this research article. "Cooperative Estrogen Receptor Interaction with Consensus or Variant Estrogen Responsive Elements in Vitro" Carolyn M. Klinge, Franklin V. Peale, Jr., Russell Hilf, et al.