Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Hao Xing
Date created: 2013-05-11 11:00:00
Date modified: 2015-05-08 01:14:08
pAlkB promoter in Pseudomonas putida
| Types | DnaRegion |
| Roles | promoter Regulatory |
| Sequences | BBa_M41005_sequence (Version 1) |
Description
It is an inducible promoter for alkBFGHJKL operon (alkane degradation operon). It is induced by AlkS-Hydrocarbon complex. The operon encodes different enzymes responsible for alkane degradation. Expression of the PalkB promoter is also modulated by catabolite repression depending on the carbon source being used.Notes
pAlkB is regulated by different carbon sources. When alkane is the only major source for energy in the cell, pAlkB will express the operon.Source
Van Beilen, JB, et al. "Analysis of Pseudomonas Putida Alkane-Degradation Gene Clusters and Flanking Insertion Sequences: Evolution and Regulation of the Alk Genes." Microbiology 147.6 (2001): 1621-30.Canosa, I., et al. "A Positive Feedback Mechanism Controls Expression of AlkS, the Transcriptional Regulator of the Pseudomonas Oleovorans Alkane Degradation Pathway." Molecular microbiology 35.4 (2000): 791-9.