BBa_M45180

BBa_M45180 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_M45180
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Holly Saatzer
Date created: 2016-04-25 11:00:00
Date modified: 2016-05-09 03:58:05

Ornithine decarboxylase antizyme 1



Types
DnaRegion

Roles
Coding

CDS

Sequences BBa_M45180_sequence (Version 1)

Description

OAZ1 is a member of the ODC antizyme family. OAZ1 is auto-regulated expressed by polyamine-enhanced translational frame shifting. OAZ1 negatively controls polyamine synthesis by increasing the negative feedback loop regulating ornithine decarboxylase (ODC) activity. OAZ1 inhibits ornithine decarboxylase and speeds up its detraction. This process is for theoretical reference, perhaps it could be further studied/modified for a lysine decarboxylase antizyme. ?

Notes

Theoretical, untested part

Source

HGNC HGNC 8095 genomic sequence

igem#status
Planning
 
synbiohub#ownedBy
user/james
 
synbiohub#ownedBy
user/myers
 
synbiohub#topLevel
BBa_M45180/1