BBa_M45180

BBa_M45180 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_M45180
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Holly Saatzer
Date created: 2016-04-25 11:00:00
Date modified: 2016-05-09 03:58:05

Ornithine decarboxylase antizyme 1



    • Details

    Types
    DnaRegion

    Roles
    Coding

    CDS

    Sequences BBa_M45180_sequence (Version 1)

    Description

    OAZ1 is a member of the ODC antizyme family. OAZ1 is auto-regulated expressed by polyamine-enhanced translational frame shifting. OAZ1 negatively controls polyamine synthesis by increasing the negative feedback loop regulating ornithine decarboxylase (ODC) activity. OAZ1 inhibits ornithine decarboxylase and speeds up its detraction. This process is for theoretical reference, perhaps it could be further studied/modified for a lysine decarboxylase antizyme. ?

    Notes

    Theoretical, untested part

    Source

    HGNC HGNC 8095 genomic sequence

    igem#status
    Planning
     
    synbiohub#ownedBy
    user/james
     
    synbiohub#ownedBy
    user/myers
     
    synbiohub#topLevel
    BBa_M45180/1
     

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