Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Marko Bitenc
Date created: 2007-10-21 11:00:00
Date modified: 2015-08-31 04:07:46
CMV promoter - CD4 (shortened) - TEV C
| Types | DnaRegion |
| Roles | Composite engineered_region |
| Sequences | BBa_I712083_sequence (Version 1) |
Description
Human CD4 shortened receptor fused with C-terminal half of TEV protease and Myc tag. This construct is under control of CMV promoter.Notes
CD4 (shortened) is also fused with C-terminal half of TEV protease. This construct is coexpressed with CCR5 receptor fused with N-terminal half of TEV protease (in mammalian cells). When that kind of human cells are infected with HIV virus both halves of TEV protease assemble and split protein regains its function. This principle can be used for fighting HIV infection.Source
Human CD4 is a member of the immunoglobulin superfamily.| Access | Instance | Definition |
| public public | BBa_I712082 BBa_I712078 | BBa_I712082 BBa_I712078 |
| Sequence Annotation | Location | Component / Role(s) |
| BBa_I712082 BBa_I712078 | 1,1907 1916,2290 | BBa_I712082 BBa_I712078 |