Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Ben Clarkson
Date created: 2012-07-04 11:00:00
Date modified: 2015-08-31 04:08:22
ScpxP--Short cpxP promoter
| Types | DnaRegion |
| Roles | promoter Regulatory |
| Sequences | BBa_J100073_sequence (Version 1) |
Description
The promoter for the cpxP gene in E. coli, which is involved in responses to cytoplasmic stresses (cpxP gene in E. coli). Transcription is activated by high pH via the CpxAR two-component signal transduction pathway. Alkaline pH activates CpxA, an autokinase, which then phosphorylates CpxR. CpxR then activates cpxP and degP. DegP degrades cpxP, and cpxP inhibits the autokinase activity of CpxA (CpxAR two-component signal transduction pathway in E. coli).Notes
This promoter includes 94 bp upstream from the transcription start site.Source
Cloned from E. coli genome using PCR| Sequence Annotation | Location | Component / Role(s) |
| CpxR-phosphorylated CpxR-phosphorylated CpxR-phosphorylated | 31,45 51,65 76,94 | feature/binding non_covalent_binding_site non_covalent_binding_site feature/binding non_covalent_binding_site feature/binding |