Types | DnaRegion
|
Roles | Regulatory
promoter
|
Sequences | BBa_J89000_sequence (Version 1)
|
Description
Theophylline riboswitch 12.1 is an RNA encoded regulatory element that regulates gene expression upon the binding of theophylline. When the molecule is present in the solution, the ribowitch senses it and changes its conformation, unmasking the ribosome binding site and allowing translation.
Notes
Theophylline riboswitch 12.1 is made up of an aptamer that can bind theophylline, a linker, a ribosome binding site; it ends with the first codon (ATG) of a reporter gene.
Source
Theophylline riboswitch 12.1 is a synthetic riboswitch, identified with flow cytometry-based screen in a library.