Types | DnaRegion
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Roles | engineered_region
Generator
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Sequences | BBa_K1053014_sequence (Version 1)
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Description
This hammerhead ribozyme(HHR) has trans-acting RNA(taRNA) responsive region, and this HHR responses to taR12. In absence of taR42, the HHR can self-cleave, but in presence of taR12, their capability of self-cleavage is inhibited due to hybridize with taR12 and change their structures. This HHR has taR12y in the downstream. taR12 and taR12y are orthogonal riboregulators reported by Callura et al.
Notes
The region recognizing TR-HHR in taRNA is sequestrated in HHR's extended stem I.
Source
This is composed of BBa_K1053000(taRNA responsive Hammerhead Ribozyme(TR-HHR) with RBS) & BBa_K1053010(PBAD-taR12y-DT)