| Types | DnaRegion
|
| Roles | Regulatory
promoter
|
| Sequences | BBa_K1061011_sequence (Version 1)
|
Description
Ef-1alpha promoter is a strong constitutive promoter that drive the expression of elongation factor -1α.It has been widely used in constructing mammalian cell-based circuit, especially useful for construction of long-term circuit in some cells including iPS cells and Jurkat cells in which the strong promoter CMV may be silenced.
Notes
The promoter that we submit comes from the lentivector constructed by Lei Xiao???s lab. It is a truncated version of the full-length human EF-1α promoter, including a cPPT/CTS fragment which can enhance the transduction efficiency of lentivectors.
Source
We clone this part from the plasmid provided by Lei Xiao's lab.
