| Types || |
| Roles |
| Sequences || BBa_K1088005_sequence (Version 1)|
DescriptionThis sequence is a copy of the sequence 70,387 -> 71,265 in E. coli K-12 MG1655 which is the coding sequence of the pBAD repressor araC.
The "arabinose regulator," AraC, is a transcription factor that regulates transcription of several genes and operons involved in arabinose catabolism and transport. It coregulates with another transcriptional regulator, CRP; both are transcription factors involved in l-arabinose degradation. These regulators bind cooperatively to activate transcription of five operons related to transport, catabolism, and autoregulation of l-arabinose. Transcription of these operons is induced when E. coli is grown in the absence of glucose and when the physiological inducer, l-arabinose, binds to the AraC regulator. In the absence of glucose, cellular cyclic AMP levels are high and cyclic AMP forms a dimeric complex with CRP to coregulate with AraC.
For more info go to http://ecocyc.org/ECOLI/NEW-IMAGE?type=GENE&object=EG10054
NotesThe part was amplified from chromosomal DNA with primers carrying prefix and suffix overhangs
SourceE. coli K-12 MG1655