| Types | DnaRegion
|
| Roles | CDS
Coding
|
| Sequences | BBa_K1199043_sequence (Version 1)
|
Description
The enzyme DhaA is of particular interest because it enables a very slow conversion of the toxic artificial compound and suspected human carcinogen 1,2,3-trichloropropane (TCP) to 2,3-dichloropropane-1-ol under laboratory conditions .And DhaA31 is a mutant of DhaA ,DhaA31 has large aromatic residues at two of the three randomized positions and at two positions modified by site-directed mutagenesis. These changes enhance activity towards TCP by decreasing the accessibility of the active site to water molecules, thus promoting the formation of an activated complex.
Notes
no restriction site contained
Source
DhaA is from Rhodococcus sp hydrolyzes
