Types | DnaRegion
|
Roles | Coding
CDS
|
Sequences | BBa_K1255000_sequence (Version 1)
|
Description
"NhaS is proposed to be a sodium binding protein that can enhance the Na+ -resistance of antiporter- deficient strains by increasing the availability of Na+ to the integral membrane antiporters on the cytoplasmic side of the membrane and by sequestering Na+ while rate-limiting efflux mechanisms catalyze extrusion of the cation." (Krulwich et al. 1994)
"The NhaS protein enhances resistance of bacteria into which the nhaS gene has been introduced, to Na+ by sequestering Na+ and reducing its cytotoxicity." (Krulwich et al. 1994)
NhaS is protein that binds to sodium ions and enhance the bacteria's resistance up to 15% to high saline conditions.
Notes
The original genomic sequence was optimized for expression in E. coli.
IVEY Mark, KRULWICH Terry. (1994) Sodium ion binding proteins. From http://www.google.com.mx/patents/US5346815.
Source
NhaS comes from Bacillus Firmus.