BBa_K1315005

BBa_K1315005 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_K1315005
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Dimitrios Michailidis
Date created: 2014-09-24 11:00:00
Date modified: 2015-05-08 01:09:50

The clp gene from Xanthomonas campestris



Types
DnaRegion

Roles
Coding

CDS

Sequences BBa_K1315005_sequence (Version 1)

Description

c-di-GMP Repressed DNA Binding Protein (Clp)
Quorum sensing and bacterial cell signalling are mechanisms known to be utilised by bacteria to regulate their virulence. The RpfC-RpfG sensory system has been found to activate the production of virulence factors like extracellular enzymes and polysaccharides in Xanthomonas campestris. It has been also suggested that this system is involved in linking environmental stimuli, including DSF, with pathogenicity in Xanthomonas campestris. DSF is a cis-unsaturated fatty acid from the DSF family. The RpfC-RpfG two-component system is the most well understood one and is present in all Xanthomonads.
http://www.ncbi.nlm.nih.gov/pubmed/?term=r+ryan+dsf+family http://www.ncbi.nlm.nih.gov/pubmed/?term=A+two-component+system+involving+an+HD-GYP+domain+protein+links+cell%E2%80%93cell+signalling+to+pathogenicity+gene+expression+in+Xanthomonas+campestris

Notes

The sequence had 1 PstI site that was mutated out by site-directed mutagenesis.

Source

The source of this part is Xanthomonas campestris pv. campestris 8004 genomic DNA which was provided by the Robert Ryan lab in the Molecular Microbiology department of the University of Dundee, UK.

Sequence Annotation Location Component / Role(s)
Clp
1,696
feature/cds CDS
igem#experience
None
 
igem#sampleStatus
In stock
igem#status
Available
 
synbiohub#ownedBy
user/james
 
synbiohub#ownedBy
user/myers
 
synbiohub#topLevel
BBa_K1315005/1